In order to understand what are liposomes, it helps to be familiar with what liposomes actually are. Liposomes are small pieces of a cellular structure (in the case of our own body, these are called lymphocytes). These pieces of cellular material have many different functions within the body, but what they typically end up doing is encapsulating and transporting various substances from the bloodstream into various parts of the body, where they play an important role. Some liposomes carry toxins, some transport nutrients, and others combine these roles in what is termed as the transport mechanisms of the cell.
A new paper published by Devarajan and colleagues at the University of Wisconsin- Madison, in the June issue of Cell Reports, highlights the role of these liposomes in the regulation of the release of two important molecules, Enkephalins, and Endorphins. These two chemicals are released through the digestive system when we eat foods that contain certain lipids, primarily those composed of liposomal CBD. However, some scientists believe that the levels of Enkephalins and Endorphins produced in the body are too high and that only a small percentage of the ingested substance gets absorbed into the body tissue.
In order to increase Enkephalin and Endorphin bioavailability, researchers at the University of Wisconsin-Madison recently discovered that cannabidiol, the compound that is found in marijuana, can increase liposome delivery. The study was performed using laboratory mice and found that when the mice were given access to two different doses of cannabidiol, they had higher levels of Enkephalins and Endorphins than when they received a standard dose of saline. What,s more, this effect was found when the mice were not given access to a standardized test substance; the researchers instead injected the mice with diluted extracts of liposomal CBD.
There are several theories as to why Enkephalins and Endorphins may play a role in the bioavailability of liposomes. One theory is that the liposomes act as a scaffold or a base for the plant-derived compounds. The liposomes would then act as a platform, allowing the CBD to enter the body and reach the specific areas that are damaged or infected. If the Enkephalins and Endorphins that are present in the liposome scaffold, which is similar in size and shape to cancer cells, were to become part of the immune system,s natural defenses, then it is possible that the body,s natural defense would be to fight off these foreign compounds instead of letting them into the cells. This could further explain why the absorption rate of liposomal CBD is so much higher when using CBD oil compared to other oils.
CBD oil liposomes can also be created by combining CBD and vitamin c in a liposome suspension. This combination has been successful in the past when combining with other ingredients to make an effective combination has not been achieved. In this case, the addition of vitamin c to help increase the stability of the liposomes and the CBD to make them more likely to enter the cell has been successful.